Association of the Ratio of Triglycerides to High-Density Lipoprotein Cholesterol Levels with the Risk of Type 2 Diabetes: A Retrospective Cohort Study in Beijing
Table 5
Subgroup analyses of the association between TG/HDL-C and incidence of type 2 diabetes mellitus in the REACTION study.
Confounding factor
Serum TG/HDL-C quintile
for trend
for interaction
Q1
Q2
Q3
Q4
Q5
Age
0.01
<60 years
1
1.67 (0.91, 3.07) 0.10
2.59 (1.47, 4.56) <0.01
3.28 (1.88, 5.70) <0.01
4.50 (2.61, 7.75) <0.01
<0.01
>60 years
1
0.96 (0.48, 1.92) 0.90
0.74 (0.36, 1.54) 0.43
1.30 (0.67, 2.54) 0.44
1.08 (0.55, 2.12) 0.82
0.50
Sex
0.53
Male
1
1.51 (0.69–3.31) 0.30
1.48 (0.68–3.22) 0.33
1.65 (0.78–3.50) 0.19
2.19 (1.05–4.57) 0.04
0.03
Female
1
1.21 (0.69–2.11) 0.50
1.75 (1.04–2.96) 0.03
2.61 (1.58–4.31) <0.01
2.97 (1.81–4.88) <0.01
<0.01
BMI
0.83
<25
1
1.43 (0.73–2.79) 0.30
1.85 (0.95–3.60) 0.07
2.39 (1.22–4.67) 0.01
3.71 (1.97–6.99) <0.01
<0.01
≥25
1
1.26 (0.68–2.35) 0.46
1.55 (0.86–2.79) 0.14
2.19 (1.25–3.83) 0.01
2.40 (1.38–4.18) <0.01
<0.01
Family history of T2DM
0.20
Yes
1
1.09 (0.50–2.34) 0.8309
1.76 (0.87–3.6) 0.1155
2.79 (1.42–5.47) 0.0029
2.18 (1.09–4.34) 0.0267
0.01
No
1
1.55 (0.88–2.73) 0.1281
1.69 (0.97–2.93) 0.0639
2.18 (1.28–3.72) 0.0041
3.31 (1.98–5.55) <0.0001
<0.01
Adjusted for age, sex, body mass index, histories of hypertension, tumors, stroke, and coronary heart disease, smoking status, alcohol intake, low-density lipoprotein cholesterol level, strenuous activity, education level, and family histories of T2DM and tumors.
