Research Article

Predictive Value of First-Trimester Glycosylated Hemoglobin Levels in Gestational Diabetes Mellitus: A Chinese Population Cohort Study

Table 3

ROC curve values of first-trimester Hba1c in the diagnosis of GDM.

HbA1cSensibility (95% CI)Specificity (95% CI)PLR (95% CI)NLR (95% CI)

>4.4100 (97.5-100.0)1.17 (0.5-2.4)1.01 (1.0-1.0)0
>4.599.31 (96.2-100.0)2.67 (1.5-4.3)1.02 (1.0-1.0)0.26 (0.03-1.9)
>4.698.61 (95.1-99.8)4.83 (3.3-6.9)1.04 (1.0-1.1)0.29 (0.07-1.2)
>4.795.83 (91.2-98.5)8.83 (6.7-11.4)1.05 (1.0-1.1)0.47 (0.2-1.1)
>4.891.67 (85.9-95.6)16.67 (13.8-19.9)1.1 (1.0-1.2)0.5 (0.3-0.9)
>4.984.72 (77.8-90.2)29 (25.4-32.8)1.19 (1.1-1.3)0.53 (0.4-0.8)
>574.31 (66.4-81.2)46.17 (42.1-50.2)1.38 (1.2-1.6)0.56 (0.4-0.7)
>5.156.94 (48.4-65.2)62.83 (58.8-66.7)1.53 (1.3-1.8)0.69 (0.6-0.8)
>5.1256.94 (48.4-65.2)63 (59.0-66.9)1.54 (1.3-1.8)0.68 (0.6-0.8)
>5.242.36 (34.2-50.9)78.83 (75.3-82.0)2 (1.6-2.6)0.73 (0.6-0.8)
>5.333.33 (25.7-41.7)89.67 (86.9-92.0)3.23 (2.3-4.5)0.74 (0.7-0.8)
>5.418.75 (12.7-26.1)94.67 (92.6-96.3)3.52 (2.2-5.7)0.86 (0.8-0.9)
>5.513.19 (8.1-19.8)97.67 (96.1-98.7)5.65 (2.9-11.0)0.89 (0.8-0.9)
>5.67.64 (3.9-13.3)98.83 (97.6-99.5)6.55 (2.6-16.6)0.93 (0.9-1.0)
>5.74.17 (1.5-8.8)99.5 (98.5-99.9)8.33 (2.1-32.9)0.96 (0.9-1.0)
>5.82.78 (0.8-7.0)99.67 (98.8-100.0)8.33 (1.5-45.1)0.98 (0.9-1.0)
>5.92.78 (0.8-7.0)99.83 (99.1-100.0)16.67 (1.9-148.0)0.97 (0.9-1.0)
>61.39 (0.2-4.9)99.83 (99.1-100.0)8.33 (0.8-91.3)0.99 (1.0-1.0)
>6.10 (0.0-2.5)100 (99.4-100.0)1 (1.0-1.0)

Note: NLR: likelihood ratio; PLR: positive likelihood ratio.