Investigation of the Mechanism of Complement System in Diabetic Nephropathy via Bioinformatics Analysis

Figure 10

The correlation analysis between complement cascade-related hub genes (C1QA, C1QB, C3, CFB, ITGB2, VSIG4, and CLU) and the expression of GFR in DN patients. (a) The expression of C1QA was negatively correlated with GFR (, ). (b) The expression of C1QB was negatively correlated with GFR (, ). (c) The expression of C3 was negatively correlated with GFR (, ). (d) The expression of CFB was positively correlated with GFR (, ). (e) The expression of ITGB2 was negatively correlated with GFR (, ). (f) The expression of VSIG4 was negatively correlated with GFR (, ). (g) The expression of CLU was negatively correlated with GFR (, ).

(a)

(b)

(c)

(d)

(e)

(f)

(g)