Investigation of the Mechanism of Complement System in Diabetic Nephropathy via Bioinformatics Analysis

Table 2

Hub genes of diabetic nephropathy.

Groups	Gene symbol	GSE30528		GSE104948		GSE47183
		LogFC	value	LogFC	value	LogFC	value
Up	FN1	1.540307		1.688679		1.411328	0.000115
	CD44	1.410913	0.00288	1.154713		1.118944	0.004117
	ITGB2	1.288601	0.000137	1.624558		1.176759	0.015233
	CCL5	1.720493	0.000615	1.281747		1.010635	0.002817
	CD163	1.973348		1.260515		2.25682	0.006126
	C1QA	1.922276		2.469202		2.643819	0.002315
	C1QB	2.204686		2.123409		2.331991	0.003483
	CYBB	1.082376		1.559454		1.081369	0.01398
	TYROBP	1.3831	0.000242	2.191158		1.720981	0.000578
	LYZ	1.529532	0.00258	2.79008		1.693295	0.000448
	CD48	1.736706	0.000071	2.1464		1.271107	0.002955
	IL10RA	1.468163	0.000276	1.928371		1.340032	0.004027
	CLEC10A	1.005234		1.197336		1.050224	0.032825
	COL1A2	2.590987		2.656871		2.275034	0.005026
	CLU	1.472253	0.000508	1.734574		1.912975	0.002851
	C3	2.679961	0.000157	2.281075		2.430408	0.017567
	IRF8	1.583247	0.000131	1.488973		1.493004	0.005593
	CD52	2.232654		2.140349		1.169746	0.007569
	TGFBI	1.32786	0.000642	2.396142		2.168562
	ALOX5	1.673735	0.00568	1.450238		1.277775	0.001606
	CD53	1.672055		1.74099		1.230233	0.012145
	VSIG4	1.576657		1.696336		1.919467	0.003
	CFB	1.720388		1.382782		1.365459	0.021665
	IGFBP3	1.033501		1.23278	0.000966	2.409502	0.002813
	LAPTM5	1.062031	0.00158	1.554621		1.238422	0.001673
	MS4A6A	1.869037		2.054775		1.959976	0.00497
	LUM	2.374619		1.843351	0.00363	3.496266	0.004413
	VCAN	1.273776	0.00177	1.33971		1.440879	0.034958
	MS4A4A	1.446755		2.039072		1.994681	0.00792
	DOCK2	1.009537	0.0028	1.457016		1.181051	0.003642
Down	ALB	-1.78623	0.00896	-2.38803	0.000092	-2.63068	0.007517
	IGF1	-2.57456		-1.6702		-1.63423