Research Article

Association of Body Fat Percentage with Time in Range Generated by Continuous Glucose Monitoring during Continuous Subcutaneous Insulin Infusion Therapy in Type 2 Diabetes

Table 1

Characteristics of study participants by body fat percentage.

VariablesAll subjects ()Normal fat group ()Overfat group () value

Age (years)0.132
Male (, %)54 (63.5%)34 (75.6%)20 (50.0%)0.018
Diabetes duration (months)72.0 (2.5-138.0)60.0 (2.5-120.0)78.0 (2.3-144.0)0.684
Insulin doses (IU/kg/d)0.307
Bolus/basal ratio0.269
SBP (mmHg)0.112
DBP (mmHg)0.528
BMI (kg/m2)<0.001
Waist circumference (cm)<0.001
Hip circumference (cm)0.002
Waist-to-hip ratio (WHR)0.026
TC (mmol/L)5.0 (4.2-5.9)4.8 (3.9-5.4)5.3 (4.3-6.1)0.066
TG (mmol/L)1.8 (1.2-3.0)1.5 (1.1-3.0)1.9 (1.3-3.2)0.297
HDL-C (mmol/L)0.990
LDL-C (mmol/L)0.191
HbA1c (%)0.305
Fasting C-peptide (ng/mL)1.6 (1.2-2.8)1.4 (1.1-2.3)2.0 (1.2-3.3)0.101
Postprandial C-peptide (ng/mL)2.8 (1.9-4.7)2.6 (1.8-4.5)2.9 (2.2-5.3)0.127
72 h MBG (mmol/L)0.001
SDBG (mmol/L)3.3 (2.8-3.9)3.3 (2.7-3.8)3.4 (2.8-4.1)0.489
CV (%)0.033
MAGE (mmol/L)0.139
MODD (mmol/L)3.3 (2.4-3.9)3.0 (2.2-3.8)3.5 (2.5-4.2)0.109
TIR (%)0.004
TAR (%)0.001
TBR (%)0 (0-1.7)0.4 (0-8.0)0 (0-0.9)0.003
Muscle quantity (kg)0.305
Body fat quantity (kg)<0.001
Body fat percentage<0.001
Visceral fat area (cm2)<0.001
Hypertension (, %)38 (44.7%)13 (28.9%)25 (62.5%)0.002
Fatty liver (, %)55 (64.7%)24 (55.8%)31 (83.8%)0.007
Current smoker (, %)22 (25.9%)15 (34.1%)7 (17.5%)0.084

Data are represented as , median [25th to 75th percentile range], or number (%). DBP: diastolic blood pressure; SBP: systolic blood pressure; BMI: body mass index; TC: total cholesterol; TG: triglycerides; HDL-C: high density lipoprotein cholesterol; LDL-C: low density lipoprotein cholesterol; 72 h MBG: 72 h mean blood glucose concentration; SDBG: standard deviation of blood glucose; CV: coefficient of variation; MAGE: mean amplitude of glycemic excursions; MODD: mean of daily differences; TIR: time in range; TAR: time above range; TBR: time below range.