Adenosine A1 Receptor Deficiency Aggravates Extracellular Matrix Accumulation in Diabetic Nephropathy through Disturbance of Peritubular Microenvironment

<div>Costaining of A1AR and CD34 in kidney tissues of GML and DN patients by immunofluorescent staining. (a) A1AR was mainly expressed on the renal proximal tubular cell membrane, while CD34 was expressed on microvascular cells of GML patients. (b) A1AR and CD34 were colocated at the brush border of proximal tubule cells and peritubular capillaries in DN patients by immunofluorescent staining. 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Bar width: 50 <i>μ</i>m.</div>

Journal of Diabetes Research

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Figure 2

Figure 2: Adenosine A1 Receptor Deficiency Aggravates Extracellular Matrix Accumulation in Diabetic Nephropathy through Disturbance of Peritubular Microenvironment 

Figure 2 | Adenosine A1 Receptor Deficiency Aggravates Extracellular Matrix Accumulation in Diabetic Nephropathy through Disturbance of Peritubular Microenvironment 