Research Article

Prognostic Value of Atherosclerotic Extent in Diabetic Patients with Nonobstructive Coronary Artery Disease

Table 2

Univariate and multivariate analyses of clinical profile and CCTA findings for major cardiovascular events.

Univariable HR (95% CI) value
Multivariable HR (95% CI) value

Age (years)1.04 (1.01-1.07)0.0091.03 (1.00-1.07)0.027
Male0.75 (0.43-1.32)0.3250.84 (0.47-1.51)0.556
BMI (kg/m2)1.03 (0.96-1.11)0.388
Cardiac risk factors
 Hypertension1.23 (0.67-2.25)0.505
 Hypercholesterolemia1.42 (0.80-2.54)0.231
 Current smoker0.95 (0.50-1.82)0.876
 Family history of CAD0.69 (0.33-1.42)0.310
CCTA findings
 High-risk plaque11.66 (5.45-24.95)<0.00110.94 (5.00-23.92)<0.001
 Leiden risk score1.06 (1.00-1.13)0.055
 Segment involvement score1.17 (1.00-1.36)0.048
CAD severity ()
 NormalReferenceReference
 Nonobstructive 1.86 (0.70-5.00)0.2161.56 (0.58-4.22)0.379
 Nonobstructive 4.06 (1.56-10.56)0.0042.94 (1.11-7.79)0.031

Data in parentheses are 95% confidence intervals. In this analysis, gender and variables with significant () impact on survival at a univariable level entered the multivariable model. HR: hazard rate; CAD: coronary artery disease; CCTA: coronary computed tomography angiography; BMI: body mass index.