Skin Advanced Glycation End Products among Subjects with Type 2 Diabetes Mellitus with or without Distal Sensorimotor Polyneuropathy

Table 2

AGEs in relation to the severity of DSPN.

	AGEs (single)	value	AGEs (triplicate)	value
NDS		<0.001		<0.001
No DSPN ()
Mild DSPN ()
Moderate/severe DSPN ()
Multiple comparisons
No DSPN vs. mild DSPN	—	<0.001	—	<0.001
No DSPN vs. moderate/severe DSPN	—	<0.001	—	<0.001
Mild DSPN vs. moderate/severe DSPN	—	0.500	—	0.484
VPT		<0.001		<0.001
Normal ()
Mildly impaired ()
Severely impaired ()
Multiple comparisons
Normal vs. mildly impaired	—	0.001	—	0.001
Normal vs. severely impaired	—	<0.001	—	<0.001
Mildly impaired vs. severely impaired	—	0.010	—	0.005

AGEs: advanced glycation end products; DSPN: distal sensorimotor polyneuropathy; NDS: neuropathy disability score; VPT: vibration perception threshold.