The Effectiveness of Traditional Chinese Medicine Jinlida Granules on Glycemic Variability in Newly Diagnosed Type 2 Diabetes: A Double-Blinded, Randomized Trial

Table 1

Baseline characteristics of the subjects in the study.

Variable	Group A	Group B	Group C	Group D	F value	P value
Samples (n)	35	34	36	33
Age (years)	56.53 ± 9.18	51.59 ± 10.31	56.00 ± 9.47	54.57 ± 10.54	1.733	0.163
Sex (male/female)	23/12	25/9	24/12	22/11		0.892
BMI (kg/m2)	25.69 ± 3.24	25.40 ± 3.97	26.60 ± 3.42	25.74 ± 2.73	0.830	0.480
FPG (mmol/L)	8.77±1.53	8.89±2.15	8.65±1.48	8.33±1.46	0.667	0.574
2h-PG (mmol/L)	13.60±2.83	14.35±3.36	13.79±2.48	13.26±2.86	8.834	0.478
HbA1c (%)	7.88 ± 0.78	7.83 ± 0.69	7.94 ±0.63	8.09 ±0.88	0.731	0.535
FINS (mU/L)	13.73±7.58	14.42±10.31	14.65±7.92	12.50±6.99	0.455	0.714
2h-INS(mU/L)	63.45±47.01	69.40±58.95	60.48±31.76	46.20±33.54	1.663	0.178
SBP(mmHg)	136.06±13.32	136.38±15.89	137.28±18.39	131.30±15.56	0.958	0.415
DBP(mmHg)	83.06±7.64	84.15±8.99	84.61±12.41	80.42±9.65	1.220	0.305
Triglyceride (mmol/L)	1.66 ± 0.80	2.17 ± 1.39	1.81 ± 0.91	2.15 ±2.12	1.136	0.337
Total cholesterol (mmol/L)	4.91 ± 1.03	5.17 ± 0.91	5.10± 1.00	5.32±1.03	0.966	0.411
LDL-C (mmol/L)	3.18 ± 1.01	2.97 ± 0.86	3.19 ± 0.81	3.30 ±0.97	0.742	0.529
HDL-C (mmol/L)	1.13 ± 0.23	1.15± 0.26	1.16 ± 0.28	1.20 ±0.30	0.384	0.765
TCM symptom scale	7.14 ± 4.74	6.88 ±5.38	7.94 ±6.13	8.67±5.67	0.729	0.536
TIR (%)	67.15±29.29	55.47±33.29	75.44±25.42	81.87±19.89	5.661	0.001
SD	1.74±0.69	1.96±0.95	1.63±0.57	1.55±0.56	2.079	0.106
CV (%)	18.87±5.83	20.28±8.60	18.74±5.15	18.94±6.27	0.410	0.746

Group A, control group; Group B, Jinlida group; Group C, metformin group and Group D, combination with Jinlida and metformin group. BMI, body mass index; FPG, fasting plasma glucose; 2h-PG, 2-hour postprandial glucose; HbA1c, hemoglobin A1c; FINS, fasting insulin; 2h-INS, 2 hour insulin; SBP, systolic blood pressure; DBP, diastolic blood pressure; LDL-C, low density lipoprotein cholesterol; HDL-C, high density lipoprotein cholesterol; TCM, traditional Chinese medicine; TIR, time in range; SD, standard difference; CV, coefficient of variation.