Correlation between Imaging Morphological Findings and Laboratory Biomarkers in Patients with Diabetic Macular Edema

Table 2

Association between laboratory variables and hyperreflective foci on optical coherence tomography. Laboratory variables are summarized as median (IQR: interquartile range).

	HF present ()	HF absent ()	value (MWW)
Red blood cells (10^6/μl)	4.65 (0.61)	4.73 (0.91)	0.824
White blood cells (10^3/μl)	8.54 (2.10)	7.29 (2.26)	0.028
Neutrophils (10^3/μl)	5.24 (2.08)	4.37 (1.41)	0.124
Lymphocytes (10^3/μl)	2.30 (1.01)	1.91 (0.61)	0.096
Monocytes (10^3/μl)	0.63 (0.20)	0.51 (0.27)	0.260
Platelets (10^3/μl)	248 (37)	219 (78)	0.073
Hematocrit (%)	40.6 (4.1)	40.7 (3.5)	0.547
Hemoglobin (g/dl)	13.9 (1.5)	13.4 (1.5)	0.419
Monocytes/lymphocytes	0.27 (0.14)	0.29 (0.19)	0.962
Neutrophils/lymphocytes	2.15 (0.92)	2.25 (1.36)	0.937
Monocytes/HDL	0.013 (0.006)	0.011 (0.007)	0.516
Glucose (mg/dl)	198 (87)	161 (81)	0.084
HbA1c (%)	8.8 (2.5)	7.8 (1.8)	0.281
Urea (mg/dl)	37.8 (10.8)	37.5 (23.6)	0.635
Creatinine (mg/dl)	0.8 (0.2)	0.9 (0.7)	0.168
Cholesterol (mg/dl)	172 (61)	147 (56)	0.384
LDL (mg/dl)	94 (56)	80 (44)	0.310
HDL (mg/dl)	45 (14)	47 (17)	0.975
Triglycerides (mg/dl)	170 (168)	122 (89)	0.059
IL-6 (pg/ml)	3.5 (3.7)	3.8 (2.2)	0.680
Apolipoprotein A (mg/dl)	145 (35)	141 (37)	0.334
Apolipoprotein B (mg/dl)	89 (44)	77 (34)	0.228
Lipoprotein (a) (nmol/l)	28.7 (38.6)	15.4 (107.3)	0.975
Homocysteine (μmol/l)	14.7 (7.4)	17.8 (11.2)	0.141
Vitamin D (ng/ml)	19.8 (12.7)	21.6 (18.1)	0.506

HF: hyperreflective foci; MWW: Mann–Whitney–Wilcoxon’s test.