Correlation between Imaging Morphological Findings and Laboratory Biomarkers in Patients with Diabetic Macular Edema

Table 3

Association between laboratory variables and ellipsoid zone condition on optical coherence tomography. Laboratory variables are summarized as median (IQR: interquartile range).

	EZ intact ()	EZ disrupted ()	value (MWW)
Red blood cells (10^6/μl)	4.75 (0.71)	4.38 (0.53)	0.026
White blood cells (10^3/μl)	7.81 (3.01)	8.09 (2.28)	0.417
Neutrophils (10^3/μl)	4.64 (2.03)	5.29 (3.02)	0.174
Lymphocytes (10^3/μl)	2.04 (0.62)	2.18 (1.00)	0.846
Monocytes (10^3/μl)	0.54 (0.22)	0.57 (0.33)	0.818
Platelets (10^3/μl)	246 (71)	241 (31)	0.737
Hematocrit (%)	41.2 (4.4)	38.7 (3.7)	0.012
Hemoglobin (g/dl)	14.0 (1.2)	12.9 (1.3)	0.009
Monocytes/lymphocytes	0.27 (0.14)	0.28 (0.22)	0.659
Neutrophils/lymphocytes	2.25 (1.25)	2.44 (1.53)	0.548
Monocytes/HDL	0.013 (0.006)	0.013 (0.007)	>0.999
Glucose (mg/dl)	177 (87)	113 (105)	0.133
HbA1c (%)	7.6 (2.3)	9.0 (1.5)	0.331
Urea (mg/dl)	36.2 (17.4)	42.3 (18.3)	0.274
Creatinine (mg/dl)	0.8 (0.2)	1.0 (0.7)	0.143
Cholesterol (mg/dl)	153 (64)	166 (39)	0.584
LDL (mg/dl)	86 (55)	87 (43)	0.902
HDL (mg/dl)	45 (19)	50 (11)	0.584
Triglycerides (mg/dl)	131 (149)	138 (120)	0.596
IL-6 (pg/ml)	3.4 (2.1)	4.5 (8.0)	0.377
Apolipoprotein A (mg/dl)	142 (36)	143 (13)	0.750
Apolipoprotein B (mg/dl)	82 (42)	84 (25)	0.724
Lipoprotein (a) (nmol/l)	14.7 (34.8)	89.5 (188.4)	0.015
Homocysteine (μmol/l)	15.2 (8.0)	18.9 (8.7)	0.197
Vitamin D (ng/ml)	23 (18.1)	25.4 (9.8)	0.090

EZ: ellipsoid zone; MWW: Mann–Whitney–Wilcoxon’s test.