Correlation between Imaging Morphological Findings and Laboratory Biomarkers in Patients with Diabetic Macular Edema

Table 4

Association between laboratory variables and macular ischemia on fluorescein angiography. Laboratory variables are summarized as median (IQR: interquartile range).

	Macular ischemia presence ()	Macular ischemia absence ()	(MWW)
Red blood cells (10^6/μl)	4.65 (0.73)	4.70 (0.82)	0.932
White blood cells (10^3/μl)	9.0 (2.49)	7.57 (1.96)	0.096
Neutrophils (10^3/μl)	5.24 (1.96)	4.57 (2.03)	0.074
Lymphocytes (10^3/μl)	2.33 (1.87)	2.03 (0.46)	0.718
Monocytes (10^3/μl)	0.64 (0.38)	0.51 (0.19)	0.027
Platelets (10^3/μl)	243 (86)	244 (72)	0.430
Hematocrit (%)	40.5 (6.4)	40.7 (5.3)	0.503
Hemoglobin (g/dl)	13.2 (1.4)	13.9 (1.4)	0.345
Monocytes/lymphocytes	0.29 (0.21)	0.27 (0.14)	0.159
Neutrophils/lymphocytes	2.15 (2.95)	2.25 (0.99)	0.718
Monocytes/HDL	0.016 (0.010)	0.011 (0.004)	0.019
Glucose (mg/dl)	198 (219)	167 (62)	0.606
HbA1c (%)	9.4 (3.0)	7.4 (1.8)	0.074
Urea (mg/dl)	40 (16.8)	35.8 (20)	0.154
Creatinine (mg/dl)	0.8 (0.5)	0.8 (0.2)	0.889
Cholesterol (mg/dl)	172 (80)	147 (55)	0.216
LDL (mg/dl)	98 (68)	80 (43)	0.287
HDL (mg/dl)	43 (16)	48 (19)	0.390
Triglycerides (mg/dl)	211 (190)	128 (70)	0.198
IL-6 (pg/ml)	4.2 (6.2)	3.0 (2.5)	0.149
Apolipoprotein A (mg/dl)	141 (33)	143 (34)	0.606
Apolipoprotein B (mg/dl)	93 (63)	81 (33)	0.363
Lipoprotein (a) (nmol/l)	34.7 (92.6)	15.4 (59.6)	0.363
Homocysteine (μmol/l)	17.8 (6.8)	15.7 (8)	0.731
Vitamin D (ng/ml)	17.9 (13)	21.6 (12.3)	0.668

MWW: Mann–Whitney–Wilcoxon’s test.