Evaluation of the Association between Obesity Markers and Type 2 Diabetes: A Cohort Study Based on a Physical Examination Population

Table 3

Results of Cox proportional risk regression model analysis of the relationship between different obesity markers and the development of T2DM.

	New cases/total ()	Incidence density (%)	Model 1	Model 2	Model 3
LAP
Q1 (<4.97)	27/3821	0.71	1	1	1
Q2 (4.97-10)	36/3796	0.95	1.39 (0.85-2.29)	1.2 (0.73-1.99)	1.09 (0.66-1.81)
Q3 (10-19.76)	76/3795	2	2.91 (1.88-4.51)	2.23 (1.42-3.48)	1.78 (1.13-2.81)
Q4 (>19.76)	233/3794	6.14	8.56 (5.75-12.75)	6.1 (4.02-9.25)	3.94 (2.55-6.09)
for linear trend			<0.001	<0.001	<0.001
VAI
Q1 (<0.46)	30/3799	0.79	1	1	1
Q2 (0.46-0.74)	34/3799	0.89	0.97 (0.59-1.58)	0.86 (0.52-1.4)	0.78 (0.48-1.27)
Q3 (0.74-0.1.26)	88/3799	2.32	2.44 (1.61-3.7)	1.94 (1.28-2.95)	1.59 (1.04-2.42)
Q4 (>1.26)	220/3798	5.79	6 (4.1-8.79)	4.23 (2.86-6.26)	2.85 (1.91-4.25)
for linear trend			<0.001	<0.001	<0.001
BRI
Q1 (<2.12)	27/3802	0.71	1	1	1
Q2 (2.12-2.65)	44/3801	1.16	1.79 (1.11-2.9)	1.55 (0.96-2.51)	1.43 (0.88-2.32)
Q3 (2.65-3.26)	75/3802	1.97	2.99 (1.93-4.64)	2.26 (1.44-3.53)	1.8 (1.14-2.83)
Q4 (>3.26)	226/3801	5.95	9.59 (6.43-14.29)	6.77 (4.49-10.2)	4.5 (2.93-6.91)
for linear trend			<0.001	<0.001	<0.001
BMI
Q1 (<19.99)	26/3803	0.68	1	1	1
Q2 (19.99-21.86)	50/3800	1.32	1.87 (1.16-3)	1.59 (0.99-2.56)	1.44 (0.89-2.32)
Q3 (21.86-23.97)	87/3802	2.29	3.22 (2.08-4.99)	2.42 (1.55-3.79)	2 (1.27-3.15)
Q4 (>23.97)	209/3801	5.5	7.93 (5.28-11.92)	5.92 (3.89-9.01)	3.87 (2.49-6.01)
for linear trend
WHtR
Q1 (<0.42)	27/3802	0.71	1	1	1
Q2 (0.42-0.46)	44/3801	1.16	1.79 (1.11-2.9)	1.55 (0.96-2.51)	1.43 (0.88-2.32)
Q3 (0.46-0.49)	75/3802	1.97	2.99 (1.93-4.64)	2.26 (1.44-3.53)	1.8 (1.14-2.83)
Q4 (>0.49)	226/3801	5.95	9.59 (6.43-14.29)	6.77 (4.49-10.2)	4.5 (2.93-6.91)
for linear trend			<0.001	<0.001	<0.001

Model 1: unadjusted; Model 2: adjusted for age, sex, smoke, and alcohol; Model 3: adjusted for model 2 plus ALT, AST, GGT, SBP, and DBP. .