Optical Coherence Tomography Angiography of Macular Perfusion Changes after Anti-VEGF Therapy for Diabetic Macular Edema: A Systematic Review

Table 5

A customized scale for assessing and comparing the quality of included studies.

Study	Prospective	More than 30 eyes included	Single anti-VEGF agent	Single eye of included patient	Both and scans used	Treatment naive	Follow-up more than 3 months	Customized VD assessment	Total score	Ref.
Ghasemi Falavarjani et al.	1	0	0	0	0	0	0	0	1	[32]
Sorour et al.	0	1	0	0	1	0	0	0	2	[33]
Hsieh et al.	0	1	1	1	0	0	0	1	4	[34]
Conti et al.	0	0	1	1	0	0	1	0	3	[35]
Michalska and Heinke	0	0	1	1	0	0	0	0	2	[36]
Zhu et al.	1	1	1	1	0	0	1	0	5	[37]
Mirshani et al.	1	0	1	0	0	0	0	1	3	[38]
Couturier et al.	1	0	0	0	0	1	0	0	2	[39]
Elnahry et al. (the IMPACT Study)	1	1	1	0	1	1	0	1	6	[40]
Pereira et al.	1	0	1	1	0	0	1	0	4	[41]
Elnahry et al.	1	0	1	0	0	1	1	0	4	[12]
Barash et al.	0	0	0	1	0	0	0	0	1	[42]
Statler et al.	1	0	1	1	0	0	1	0	4	[43]
Golshani et al. (SWAP-TWO study)	1	0	1	1	0	0	1	0	4	[44]
Busch et al.	0	0	1	1	0	1	1	0	4	[45]
Dastiridou et al.	1	0	1	1	0	0	0	0	3	[46]

The presence of an item amounted to a score of one while its absence amounted to a score of zero. Eight items were scored for each study; thus, the maximum score possible for a study was 8. A higher score meant a higher quality.