Parameters Detection method Reference values Clinical significance Erythrocyte count Automatic blood cell analyzer Male: Reflects the number of erythrocytes in the body Hb concentration (Hb) Automatic blood cell analyzer Male: 120–170 g/L Reflects the Hb concentration of whole blood Hematocrit (Hct) Automatic blood cell analyzer Male: 0.4–0.5 Refers to the percentage of erythrocytes in the whole blood Mean corpuscular volume (MCV) Automatic blood cell analyzer Adult: 80–100 fl Refers to the average volume of erythrocytes Mean corpuscular Hb (MCH) Automatic blood cell analyzer Adult: 26–34 pg Refers to the average amount of Hb in erythrocytes Mean corpuscular Hb concentration (MCHC) Automatic blood cell analyzer Adult: 320–360 g/L Refers to the average Hb concentration in erythrocytes RBC volume distribution width (RDW) Automatic blood cell analyzer <15 Refers to the heterogenicity of the size of erythrocytes Reticulocyte count (Ret) Automatic blood cell analyzer Adult: An indicator of the hematopoietic function of the bone marrow Erythrocyte sedimentation rate (ESR) Westergren method/automatic ESR analyzer Adult: <50 years old: 0–20 mm The rate of erythrocyte sedimentation per unit time is associated with a variety of diseases RBC deformation index (RDI) Blood rheometer 0.47–0.55 The deformability of erythrocytes RBC rigidity index (RRI) Blood rheometer Male: 7.16 An indicator of erythrocyte membrane flexibility RBC aggregation index (AI) Erythrocyte electrophoretic time 1.44–3.62 An indicator of blood viscosity; often used to diagnose thrombosis Glycosylated Hb (GHb/HbA1c) Affinity chromatography/high performance liquid chromatography (HPLC) 4%–6% Reflects the body’s average blood sugar levels over the past 6–8 weeks Erythrocyte morphology Blood smear Double concave disk, the average diameter was 7.2 μ m, pale pink, one-third of the center is the physiological light staining area, and there are no abnormal structures in the cytoplasm Observe the size, morphology, and internal structure of erythrocytes Membrane fluidity Fluorescent Laurdan probe Generalized polarization (GP) within the normal range Erythrocyte membrane fluidity could provide a complementary index to monitor the development of disease
