Research Article

Risk of Gestational Diabetes Mellitus in relation to Plasma Concentrations of Fatty Acid-Binding Protein 4: A Nested Case-Control Study in China

Table 1

Baseline characteristics of subjects in the first trimester.

GDM cases ()Controls () value

Age (years)29 (28-33)29 (28-33)1.00
Gestational week at enrollment10 (9-12)10 (9-12)0.36
Parity0.90
 060.059.3
 ≥140.040.7
years (%)81.579.30.55
Prepregnancy BMI (kg/m2)22.2 (20.3-25.1)22.0 (19.9-24.8)0.45
GWG before OGTT (kg)8.6 (6.2-11.0)8.6 (6.4-10.5)0.56
Weekly PA time (MET-min/week)693 (238-1386)693 (198-1386)0.78
Daily calorie intake (kcal/d)1272 (1031-1630)1242 (936-1683)0.70
SBP (mmHg)108 (101-116)110 (102-119)0.43
DBP (mmHg)67 (62-73)67 (61-72)0.66
Fasting glucose (mmol/L)5.0 (4.8-5.0)4.8 (4.6-5.0)0.02
Fasting insulin (μU/mL)45.3 (22.4-68.8)28.1 (19.8-52.8)0.02
HOMA-IR9.8 (5.1-15.1)5.8 (4.1-11.6)0.01
Triglyceride (mmol/L)1.2 (0.9-1.4)1.0 (0.9-1.3)0.07
HDL cholesterol (mmol/L)1.7 (1.4-1.9)1.8 (1.5-1.9)0.26
ALT (U/L)13 (10-23)12 (10-19)0.33
AST (U/L)14 (13-18)15 (13-17)0.92

Data were presented as medians (interquartile ranges) or %. Abbreviations: GDM: gestational diabetes mellitus; BMI: body mass index; GWG: gestational weight gain; OGTT: oral glucose tolerance test; PA: physical activity; SBP: systolic blood pressure; DBP: diastolic blood pressure; HDL: high-density lipoprotein; ALT: alanine transaminase; AST: aspartate aminotransferase.