Characteristics Associated with Early Worsening of Retinopathy in Patients with Type 2 Diabetes Diagnosed with Retinopathy at Their First Visit: A Retrospective Observational Study

Figure 1

Rates of previous medication and new interventions in a patient with simple diabetic retinopathy (a, b) and preproliferative diabetic retinopathy (c, d). Cochran–Armitage trend test was performed, with indicating statistical significance (). The -axis classifies patients into four categories: none (1), nonsulfonylurea (2), sulfonylurea (3), or insulin (4). The width represents the number of patients classified. The -axis indicates the number of patients classified into two categories: worsening (blue) or nonworsening (red). Among patients with SDR, those who received no previous medication tended to have worsening retinopathy (a). New intervention tended to significantly intensify in worsening patients with SDR (b). Among patients with PPDR, those who received no previous medication tended to have worsening retinopathy (c).