Effect of Metformin on Anthropometric Measurements and Hormonal and Biochemical Profile in Patients with Prediabetes

Table 3

Effect of metformin on pituitary and sex hormones in prediabetic males ().

	Baseline,	After 12 months,	value
Prolactin	7.3 ± 2.4	7.9 ± 2.2	0.105
Luteinizing hormone (LH)	3.9 ± 1.7	5.1 ± 1.85	0.003
Follicle-stimulating hormone (FSH)	5.8 ± 5.3	6.2 ± 4.3	0.368
Free testosterone			0.481
Total testosterone			0.597
Estradiol			0.144
Progesterone			0.028
Sex hormone-binding globulin (SHBG)			0.852
17-OH progesterone			0.068
Androstendione			0.598
Dehydroepiandrostenedione-sulphate (DHEAS)			0.489