Research Article
Clinical Implications of the Coexistence of Anemia and Diabetes Mellitus in the Elderly Population
Table 3
Clinical characteristics of diabetic patients with and without anemia.
| | Characteristics | Diabetes
| Diabetes with anemia
| Diabetes without anemia
| value |
| | Level of hemoglobin in the blood | | Female (g/dL), | | | | <0.001 | | Male (g/dL), | | | | <0.001 |
| | Other laboratory tests | | WBC (109/L), | | | | 0.312 | | RBC (1012/L), | | | | 0.301 | | PLT (109/L), | | | | 0.288 | | ESR (mm/h), | | | | 0.034 | | CRP (mg/L), | | | | 0.288 |
| | eGFR level(%) | | 46 (20.5) | 16 (34.04) | 30 (16.95) | 0.010 | | 178 (75.5) | 31 (65.96) | 147 (83.05) | 0.010 |
| | Comorbidities(%) | | Hypertension | 232 (94.7) | 51 (96.2) | 181 (94.3) | 0.582 | | Hypertension with complications | 170 (69.4) | 48 (90.6) | 122 (63.5) | 0.001 | | Coronary heart disease | 121 (49.4) | 31 (58.5) | 90 (46.9) | 0.265 | | Heart failure | 33 (13.5) | 17 (32.1) | 16 (8.3) | 0.092 | | Atrial fibrillation | 29 (11.8) | 10 (18.9) | 19 (9.9) | 0.495 | | PAD | 25 (10.2) | 13 (24.53) | 12 (6.25) | 0.004 | | Venous thromboembolism | 6 (2.4) | 2 (3.8) | 4 (2.1) | 0.903 | | Thyroid diseases | 47 (19.2) | 14 (26.4) | 33 (17.2) | 0.469 | | Pulmonary disease | 25 (10.2) | 8 (15.1) | 17 (8.9) | 0.640 | | Asthma | 13 (5.3) | 3 (5.7) | 10 (5.2) | 0.976 | | COPD | 8 (3.3) | 3 (5.7) | 5 (2.6) | 0.826 | | Chronic kidney disease | 41 (16.7) | 18 (34) | 23 (12) | 0.090 | | Chronic liver diseases | 15 (6.1) | 10 (18.9) | 5 (2.6) | 0.384 | | Rheumatic diseases | 0 (0) | 0 (0) | 0 (0) | — | | Dementia | 6 (2.4) | 2 (3.8) | 4 (2.1) | 0.903 | | Cancer | 29 (11.8) | 13 (24.5) | 16 (8.3) | 0.232 |
| | Drugs(%) | | Insulin | 60 (24.5) | 20 (37.7) | 40 (20.8) | 0.011 | | Metformin | 91 (37.1) | 20 (37.7) | 71 (37) | 0.951 | | ACE inhibitors | 111 (45.3) | 38 (71.7) | 73 (38) | <0.001 | | Aspirin | 106 (43.3) | 36 (67.9) | 70 (36.5) | <0.001 | | DOACs+VKA | 27 (11) | 13 (24.5) | 14 (7.3) | 0.001 |
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ALT: aminotransferase alanine; AST: aminotransferase aspartate; COPD: chronic obstructive pulmonary disease; CRP: C-reactive protein; DOACs: direct oral anticoagulants; ESR: erythrocyte sedimentation rate; PAD: peripheral artery disease; PLT: platelets; VKA: vitamin K antagonists; WBC: white blood cells; RBC: red blood cells.
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