Research Article

Tacrolimus Protects Podocytes from Apoptosis via Downregulation of TRPC6 in Diabetic Nephropathy

Table 1

General data of rats after 8 weeks of treatment ().

CharacteristicsNC ()DM ()FK ()

SBP (mmHg)aa
BM (kg)aa
KM/BM (g/kg)aab
FBG (mmol/L)aa
FINS (mU/L)
ISIaa
CCr (mL/min)aa
TG (mmol/L)aa
TC (mmol/L)aa
ALT (U/L)
AST (U/L)
WBC (×109/L)

a vs. NC group; b vs. DM group. SBP: systolic blood pressure; BM: body mass; KM/BM: kidney mass/body mass ratio; FBG: fasting blood glucose; FINS: fasting serum insulin; ISI: insulin sensitivity index; CCr: creatinine clearance; TG: triglyceride; TC: total cholesterol; ALT: alanine transaminase; AST: aspartate transaminase; WBC: white blood cell; NC: normal control group; DM: diabetes mellitus group; FK: FK506 group.