Exosomes Secreted by Umbilical Cord Blood-Derived Mesenchymal Stem Cell Attenuate Diabetes in Mice

Figure 5

STZ treatment-induced diabetes in mice. (a) Line graph showing blood glucose levels in diabetic mice compared to the control animals over the experiment period (/group). (b) Line graph showing body weight in the diabetic group compared to the control group (/group). (c) (i) Representative images of histological analysis of H&E () in the diabetic and control groups showing the altered pancreatic morphology. The lower panel shows images of H&E staining with multiple islets (low magnification, ). (c) (ii) Histogram representing the number of healthy and damaged cells in islets counted on three different sections (five random fields) in the diabetic group and control group. (d) Histogram representing insulin levels in pancreatic tissue of the diabetic and control groups. Data are shown as the (/group). The significance of differences between mean values was estimated by nonparametric Student’s -test (unpaired, two-tailed). and compared to control animals.

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