Network Pharmacology and Molecular Docking Study on the Potential Mechanism of Yi-Qi-Huo-Xue-Tong-Luo Formula in Treating Diabetic Peripheral Neuropathy

Figure 1

Workflow of the network pharmacology of YQHXTLF in the treatment of DPN. First, the effective active compounds of YQHXTLF were screened from the TCMSP. Relevant targets of DPN were summarized by searching databases. The intersection targets of compound targets and disease targets were obtained soon. Secondly, the interaction net between the compounds and the filtered targets was established. These key targets were analyzed by PPI analysis, functional analysis, and molecular docking verification. Finally, the key genes were used to find the biologic pathway and explain the therapeutic mechanism by network pharmacology analysis.