Potential Mechanisms of Triptolide against Diabetic Cardiomyopathy Based on Network Pharmacology Analysis and Molecular Docking

Figure 1

The procedures of the systematic strategies to elucidate the mechanisms of triptolide in the treatment of DCM. Targets related to triptolide and DCM were collected from online databases. The common targets of triptolide treating DCM were identified. Then, KEGG pathway enrichments were performed, and a network of triptolide-targets-KEGG was constructed. Finally, molecular dockings between triptolide and candidate target proteins (STAT3, VEGFA, FOS, TNF, TP53, and TGFB1) were conducted.