Potential Mechanisms of Triptolide against Diabetic Cardiomyopathy Based on Network Pharmacology Analysis and Molecular Docking

Figure 8

Molecular models of triptolide binding to the predicted targets (a) STAT3 (PDB: 6NJS), (b) (PDB:3V2A), (c) FOS (PDB:1A02), (d) TNF (PDB:5M2J), (e) TP53 (PDB: 6RZ3), and (f) TGFβ1 (PDB: 4KV5). The yellow dashed lines show H-bonds, and the red dashed lines show π-π interactions, with interaction distances indicated above the lines.

(a)

(b)

(c)

(d)

(e)

(f)