Residual β-Cell Function in Type 1 Diabetes Followed for 2 Years after 3C Study

Figure 2

Decline of stimulated C-peptide over 2 years (from v0 to v8). The difference of C-peptide between v8 and v0 by self-comparison in T1DM with different diabetes duration was processed with logarithm in order to reflect the changes of islet β-cell function intuitively. Among those with a duration of ≤5 years, a log-linear decline of stimulated C-peptide was observed during individuals with diabetes duration 0 to 5 years (). However, among those with a duration of ≥5 years, changes of stimulated C-peptide levels were irregular. V0: the 0th visit; V8: the 8th visit.