FABP4 and I-FABP Levels in Pregnant Women Are Associated with Body Mass Index but Not Gestational Diabetes
Table 1
Clinical parameters of patients with GDM and healthy pregnant control women.
Pregnancy parameter
GDM,
Controls,
Mann–Whitney
Median
(25%-75%)
Median
(25%-75%)
value
Age (years)a
30.5
(28.0-35.0)
31.1
(27.25-31.0)
0.87
Gestational weeka
27.07
(25.57-28.21)
25.86
(24.75-26.96)
0.01
BMI (kg/m2)
25.53
(22.56-29.89)
24.77
(22.96-28.97)
0.79
FABP4 level (pg/ml)
8030
(2885-15784)
9403
(5515-13147)
0.67
I-FABP level (pg/ml)
540.0
(199.4-905.6)
545.0
(322.5-756.55)
0.6
Fasting glucose (mmol/l)
5.0
(4.7-5.27)
4.5
(4.22-4.7)
<0.0001
60 glucose (mmol/l)
10.15
(7.75-10.78)
6.85
(5.4-7.75)
<0.0001
120 glucose (mmol/l)
7.4
(5.82-8.7)
5.85
(5.1-6.47)
0.0001
C-peptide (nmol/l)b
0.72
(0.60-0.93)
0.71
(0.54-0.84)
0.13
IL-6 (pg/ml)c
2.55
(1.14-3.69)
1.41
(0.89-1.90)
0.1
TNF-α (pg/ml)d
2.97
(2.21-4.91)
3.71
(2.64-6.92)
0.31
Adiponectin (μg/ml)d
14.28
(9.61-32.25)
22.54
(15.01-31.87)
0.32
Leptin (ng/ml)d
28.97
(23.39-40.65)
25.44
(18.53-39.88)
0.49
Resistin (ng/ml)e
33.08
(20.68-44.81)
31.99
(22.53-38.06)
0.85
EV IgA (EIU)
12.35
(1.92-27.80)
9.95
(4.25-28.33)
0.91
EV IgG (EIU)
7.55
(2.1-19.28)
11.7
(0.1-23.80)
0.48
Postpartum parameters
Fasting glucose (mmol/l)
4.95
(4.72-5.1)
4.70
(4.3-5.0)
0.009
C-peptide (nmol/l)
0.59
(0.50-0.75)
0.61
(0.47-0.74)
0.82
Triglycerides (mmol/l)
0.89
(0.61-1.13)
0.77
(0.68-1.20)
0.83
Cholesterol (mmol/l)f
5.4
(4.5-6.1)
5.05
(4.32-5.87)
0.38
HDL cholesterol (mmol/l)
1.65
(1.43-2.07)
1.68
(1.39-1.95)
0.5
LDL cholesterol (mmol/l)
3.58
(2.72-4.39)
3.25
(2.60-3.68)
0.16
aContinuous data is presented as median (25%-75% percentile) value. bData available for 40 GDM and 39 control women. cData available for 9 GDM and 26 control women. dData available for 12 GDM and 26 control women. eData available for 9 GDM and 29 control women. fData available for 39 GDM and 40 control women.
