GLP-1 RA Improves Diabetic Retinopathy by Protecting the Blood-Retinal Barrier through GLP-1R-ROCK-p-MLC Signaling Pathway

Figure 4

Reduction of albumin leakage and MMP-9/VEGF expression and increasing of ZO-1/Occludin expression through GLP-1RA treatment. (a) Western blot analysis of retinal albumin leakage in four groups. (b, c) Immunofluorescence and immunohistochemistry analysis of retinal MMP-9/VEGF/ZO-1/Occludin expression in four groups and histogram comparisons (40×). Annotation: compared with the normal group, , , and ; compared with the DM group, ^#, ^##, and ^###.

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