Autoantibodies to Zinc Transporter 8 and SLC30A8 Genotype in Type 1 Diabetes Childhood: A Pioneering Study in North Africa

Table 2

The effect of the inclusion of ZnT8-Ab assays in the panel of routinely auto-Abs on the sensitivity for beta-cell autoimmunity in type 1 diabetes (T1D) newly diagnosed children.

		Diabetic auto-Ab positive individual (1 auto-Ab)	Diabetic auto-Ab positive individual (≥1 auto-Ab)	Diabetic auto-Ab positive individual (≥2 auto-Ab)	Diabetic auto-Ab negative individuals
ICA, GADA, and IA-2A tested	No inclusion of ZnT8-Ab	61 (39.10%)	134 (85.90%)	73 (46.79%)	22 (14.10%)
	Inclusion of ZnT8-Ab	44 (28.21%)	140 (89.74%)	96 (61.54%)	16 (10.26%)
	value	0.04	0.30	0.008	0.30