Evidence and Potential Mechanisms of Traditional Chinese Medicine for the Adjuvant Treatment of Coronary Heart Disease in Patients with Diabetes Mellitus: A Systematic Review and Meta-Analysis with Trial Sequential Analysis

Table 3

The subgroup analysis of blood lipids and blood glucose.

Outcomes	No. of studies	No. of experiment	No. of control	MD	95% CI	value	(%)
TC
Total	13	1141	1097	-1.03	-1.46, -0.60	<0.001	95.2
Subgroup: follow-up
2 months	3	168	160	-1.41	-2.67, -0.15	<0.001	96.1
3 months	8	541	526	-1.02	-1.61,-0.42	<0.001	95.1
6 months	1	75	75	-0.83	-1.16, -0.49
4 years	1	285	306	-0.29	-0.45, -0.13
Subgroup: prescription
Xuezhikang	2	373	352	-0.63	-1.34, 0.07	<0.001	92.1
TG
Total	13	1141	1097	-0.93	-1.32, -0.53	<0.001	94.3
Subgroup: follow-up
2 months	3	168	160	-1.02	-2.06, -0.03	<0.001	94.8
3 months	8	541	526	-1.03	-1.54, -0.53	<0.001	93.3
6 months	1	75	75	-0.697	-1.026, -0.367
4 years	1	285	306	-0.062	-0.223, 0.099
Subgroup: prescription
Xuezhikang	2	373	352	-0.46	-1.27,0.35	<0.001	94.2
HDL
Total	11	1068	1024	0.72	0.41, 1.02	<0.001	90.7
Subgroup: follow-up
2 months	1	68	60	1.39	1.01, 1.78
3 months	8	619	604	0.8	0.54, 1.06	<0.001	79.5
6 months	1	75	75	0.096	-0.224, 0.417
4 years	1	306	285	0.141	-0.02,0.3
Subgroup:prescription
Xuezhikang	2	373	352	0.29	-0.06, 0.63	0.066	70.5
LDL
Total	14	1243	1199	-1.20	-1.61, -0.79	<0.001	95.2
Subgroup: follow-up
2 months	2	110	118	-0.88	-1.15, -0.6	0.711	0
3 months	10	744	729	-1.38	-1.95, -0.81	<0.001	95.8
6 months	1	75	75	-0.898	-1.23, -0.56
4 years	1	306	285	-0.459	-0.62, -0.3
Subgroup: prescription
Xuezhikang	2	373	352	-0.49	-0.64, -0.34	0.337	0
FBG
Total	13	1143	1045	-0.5	-0.67, -0.33	<0.001	72.4
Subgroup: follow-up
2 months	4	358	275	-0.44	-0.73, -0.15	0.04	64.9
3 months	8	725	710	-0.49	-0.7, -0.27	<0.001	76.5
6 months	1	60	60	-0.886	-1.26, -0.51
Subgroup: prescription
Tongxinluo	2	303	303	-0.43	-0.86, -0.01	0.009	85.2
HbA1c
Total	9	679	664	-1.159	-1.85, -0.47	<0.001	96.9
Subgroup: follow-up
3 months	8	619	604	-0.95	-1.63, -0.28	<0.001	96.6
6 months	1	60	60	-2.85	-3.36,-2,3
2hPG
Total	10	948	850	-0.58	-1, -0.16	<0.001	94.5
Subgroup: follow-up
2 months	4	358	275	-0.42	-0.72, -0.11	0.02	68.4
3 months	6	575	590	-0.69	-1.37, -0.01	<0.001	96.6
Subgroup: prescription
Tongxinluo	2	303	303	-1.42	-3.33, 0.49	<0.001	99