The Association of Postprandial Triglyceride Variability with Renal Dysfunction and Microalbuminuria in Patients with Type 2 Diabetic Mellitus: A Retrospective and Observational Study

Table 2

Multivariate Cox’s proportional hazard regression model for the association between postprandial TG variability and eGFR decline (primary endpoint).

HR [95% CI] value
Model 1	1.69 [1.15-2.52] 0.0076	1.73 [1.18-2.57] 0.0052	1.64 [1.12-2.43] 0.0110
Model 2	1.61 [1.05-2.51] 0.0276	1.66 [1.09-2.58] 0.0193	1.56 [1.02-2.41] 0.0388
Model 3	1.58 [1.03-2.46] 0.0351	1.63 [1.06-2.52] 0.0251	1.54 [1.01-2.37] 0.0463
Model 4	1.62 [1.05-2.53] 0.0284	1.66 [1.08-2.58] 0.0218	1.59 [1.04-2.47] 0.0340

Model 1: adjusted for age, sex, and BMI. Model 2: adjusted for age, sex, BMI, and mean TG. Model 3: adjusted for age, sex, BMI, mean TG, baseline eGFR, and proteinuria. Model 4: adjusted for age, sex, BMI, mean TG, baseline eGFR, proteinuria, HbA1c, smoking, hypertension, and fibrates intake. TG: triglyceride; SD: standard deviation; Adj-SD: adjusted SD; MMD: maximum minus minimum difference; HR: hazard ratio; 95% CI: 95% confidence intervals; BMI: body mass index; eGFR: estimated glomerular filtration rate; HbA1c: glycated hemoglobin.