Expression of Transient Receptor Potential Channel Genes and Their Isoforms in Alpha-Cells and Beta-Cells of Human Islets of Langerhans

Figure 3

Differentially expressed TRP channel genes and their isoforms in the purified human α-cells and β-cells. (a) Differentially expressed TRP channel genes, TRPC1, TRPM3 and TRPML1 showed higher expression in the β-cells, while TRPC4 and TRPC7 showed higher expression in the α-cells. (b) Differentially expressed isoforms of TRP channel genes, TRPC4-206 showed higher expression in α-cells, while TRPM3-201, TRPM3-202, TRPM3-205, TRPM3-207, TRPM3-209, TRPM3-212, and TRPML1-204 showed higher expression in the β-cells. The color indicates the relative expression of each gene per row. Lower expression is represented in shades of blue, while higher expression is represented in shades of orange.

(a)

(b)