The Different Insulin-Sensitising and Anti-Inflammatory Effects of Palmitoleic Acid and Oleic Acid in a Prediabetes Model

Figure 5

The effect of oleic (OA) and palmitoleic acid (POA) on fatty acid profile of adipose tissue membrane phospholipids (PLs) (a) and the effect of OA and POA on relative mRNA expression and activity (desaturation indexes) of desaturase system, SCD-1, FADS1, and FADS2 (b), in adipose tissue in hereditary hypertriglyceridemic (HHTg) rats. Data are expressed as ; for each experimental group. Differences were analyzed using one-way ANOVA and LSD-Fisher’s post hoc test. denotes significance reflecting the effect of POA vs. C; # denotes significance reflecting the effect of OA vs. C; , , ; ^#, and ^##. MA: myristic acid; PA: palmitic acid; SA: stearic acid; LA: linoleic acid; DHGLA: dihomo-γ-linoleic acid; AA: arachidonic acid; n3-PUFA: n3-polyunsaturated fatty acid; αLA: α-linoleic acid; EPA: eicosapentaenoic acid; DPA: docosapentaenoic acid; DHA: docosahexaenoic acid; SCD: stearoyl-CoA desaturase; FADS: fatty acid desaturase; D9D: delta 9-desaturase; D5D: delta 5-desaturase; D6D: delta 6-desaturase; PL: phospholipid.

(a)

(b)