The Different Insulin-Sensitising and Anti-Inflammatory Effects of Palmitoleic Acid and Oleic Acid in a Prediabetes Model

Table 1

Basal metabolic and morphological characteristics of hereditary hypertriglyceridemic (HHTg) rats after oleic acid (OA) and palmitoleic acid (POA) administration.

	C	OA	POA
Body weight (g)				n.s.
EAT weight (g/100 g BW)		^##		<0.05	n.s.
PRAT weight (g/100 g BW)				n.s.
Serum TG (mmol/l)		^##		<0.01	<0.05
Serum DAG (mmol/l)				<0.01	<0.001
Serum CHOL (mmol/l)				n.s.
HDL-C (mmol/l)				n.s.
Fasting glucose (mmol/l)				n.s.
Non-fasting glucose (mmol/l)				<0.01	<0.01
AUC0-180				n.s.
Insulin (nmol/l)		^#		<0.01	n.s.
Glucagon (pg/ml)		^#		<0.05	n.s.

Data are expressed as ; for each experimental group. Differences were analyzed using one-way ANOVA and LSD-Fisher’s post hoc test. denotes the significance of oleic acid (OA)/palmitoleic acid (POA) supplementation vs. the control (C) group; denotes the significance reflecting the effect of OA vs. POA. denotes significance reflecting the effect of POA vs. C; # denotes significance reflecting the effect of OA vs. C; , , ^#, and ^##.