Stem Cell Therapy for Diabetic Foot Ulcers: Theory and Practice

Table 4

Selected studies on stem cell therapy for diabetic foot ulcer, number of enrolled subjects, dropouts, and endpoints.

Study	Enrolled ()	Participated ()	Dropout and reason	End-point control		End-point experimental
				LA (%)	CUH (%)	LA (%)	CUH (%)
[31]	96	42	13: death 2°CAD (cont.; , exp.; )	44 (20/46)	56 (26/46)	21 (8/37)	79 (29/37)
[32]	41	37	4 death (cardiopulmonary)	N/A	N/A	0	100% (37/37)
[33]	24	22	2, TRC-not met cell product criteria; Control; 1 withdrew consent; 2 died of CV events; 1 major amputation 4 weeks prior to recruitment	0	80% (8/10)	18	83% (10/12)
[34]	59	44	5; Withdrawal of consent; Not eligible; Adverse effects; Protocol violation	—	53% (9/17)	—	83% (18/22)
[35]	20	10	2 died due to other causes	N/A	N/A	0	90 (9/10)

Key: LA: limb amputation. CUH: complete ulcer healing. %: percentage.