Predictive Ability of Visit-to-Visit Variability of HbA1c Measurements for the Development of Diabetic Kidney Disease: A Retrospective Longitudinal Observational Study

Table 4

Association between degree of oxidized HSA and visit-to-visit variability of HbA1c, as assessed by a multiple linear regression model.

Index	^a		SE	value
HbA1c-SD
Q1	—	—	—	—
Q2	1.75	0.15	0.91	0.056
Q3	1.84	0.15	0.97	0.059
Q4	2.35	0.19	1.18	0.047
HbA1c-AUC
Q1	—		—	—
Q2	1.87	0.16	0.92	0.044
Q3	2.03	0.17	0.99	0.041
Q4	2.56	0.21	1.16	0.029

The quartiles of each index are represented by Q1, Q2, Q3, and Q4. The lower quartile is denoted as Q1, and the upper quartile is denoted as Q4. ^aAdjusted by sex, mean HbA1c over the 2.5-year period, duration of diabetes, SBP, eGFR, and BMI. HSA: human serum albumin; HbA1c-SD: internal standard deviation of HbA1c; HbA1c-AUC: area under the HbA1c curve; B: unstandardized partial regression coefficient; β: partial correlation coefficients; SE: standardized error SBP: systolic blood pressure; eGFR: estimated glomerular filtration rate; BMI: body mass index.