Aqueous Level of ANGPTL4 Correlates with the OCTA Metrics of Diabetic Macular Edema in NPDR

Table 5

Target cytokines affecting the OCTA Metrics in NPDR eyes .

(a)

Cytokines	Foveal RT				Parafoveal RT
	β	SE	P value	R^2	β	SE	Pvalue	R^2
ANGPTL4	4.299 × 10^-3	0.745 × 10^-3	<0.001	0.480	3.598 × 10^-3	0.572 × 10^-3	<0.001	0.523
VEGF-A	—	—	0.050		—	—	0.658

(b)

Cytokines	Foveal RV				Parafoveal RV
	β	SE	P value	R^2	β	SE	P value	R^2
ANGPTL4	3.371 × 10^-6	0.586 × 10^-6	<0.001	0.479	17.705 × 10^-6	3.285 × 10^-6	<0.001	0.447
VEGF-A	—	—	0.050		—	—	0.602

(c)

Cytokines	Whole DVD				Parafoveal DVD
	β	SE	P value	R^2	β	SE	P value	R^2
ANGPTL4	-1.705 × 10^-4	0.611 × 10^-4	0.008	0.178	-1.799 × 10^-4	0.665 × 10^-4	0.010	0.169
VEGF-A	—	—	0.148		—	—	0.238

RT: Retinal thickness; RV: retinal volume; DVD: deep vessel density; —: without data from statistics software, multivariate linear regression models, P < 0.05 was deemed to be statistically significant.