Aqueous Level of ANGPTL4 Correlates with the OCTA Metrics of Diabetic Macular Edema in NPDR
Table 5
Target cytokines affecting the OCTA Metrics in NPDR eyes .
(a)
Cytokines
Foveal RT
Parafoveal RT
β
SE
P value
R2
β
SE
Pvalue
R2
ANGPTL4
4.299 × 10-3
0.745 × 10-3
<0.001
0.480
3.598 × 10-3
0.572 × 10-3
<0.001
0.523
VEGF-A
—
—
0.050
—
—
0.658
(b)
Cytokines
Foveal RV
Parafoveal RV
β
SE
P value
R2
β
SE
P value
R2
ANGPTL4
3.371 × 10-6
0.586 × 10-6
<0.001
0.479
17.705 × 10-6
3.285 × 10-6
<0.001
0.447
VEGF-A
—
—
0.050
—
—
0.602
(c)
Cytokines
Whole DVD
Parafoveal DVD
β
SE
P value
R2
β
SE
P value
R2
ANGPTL4
-1.705 × 10-4
0.611 × 10-4
0.008
0.178
-1.799 × 10-4
0.665 × 10-4
0.010
0.169
VEGF-A
—
—
0.148
—
—
0.238
RT: Retinal thickness; RV: retinal volume; DVD: deep vessel density; —: without data from statistics software, multivariate linear regression models, P < 0.05 was deemed to be statistically significant.