Research Article

Trends in Glycemia between 2002 and 2016 among Incident Youth Cohorts Early in the Course of Type 1 Diabetes: The SEARCH for Diabetes in Youth Study

Table 1

Distribution of clinical and demographic characteristics between 2002 and 2016 among incident youth cohorts with type 1 diabetes.

20022003200420052006200820122016 value

All ()446472468453484664592377
Diabetes duration (months): mean (SD)13.0 (0.33)8.9 (0.28)8.3 (0.26)8.2 (0.25)10.3 (0.24)8.6 (0.22)10.6 (0.32)13.5 (0.50)<0.0001
Using insulin pump:
 Overall27 (6.3)52 (11.3)36 (7.8)40 (9.0)71 (15.0)90 (13.9)119 (22.6)105 (34.5)<0.0001
 Black1 (2.6)1 (2.2)0 (0.0)1 (2.1)1 (2.3)4 (6.4)8 (9.1)14 (16.7)<0.0001
 Hispanic0 (0.0)1 (2.2)2 (4.0)4 (7.4)5 (8.1)4 (3.9)12 (13.8)28 (26.9)<0.0001
 Other or Unknown0 (0.0)0 (0.0)0 (0.0)0 (0.0)0 (0.0)6 (40.0)4 (13.3)5 (29.4)0.0002
 White26 (7.7)50 (14.0)34 (9.9)35 (10.4)65 (18.5)76 (16.3)95 (27.2)58 (40.0)<0.0001
HbA1c: mean (95% CI)
 Overall7.9 (7.7, 8.0)7.7 (7.6, 7.8)7.7 (7.6, 7.9)7.6 (7.4, 7.7)8.0 (7.9, 8.2)7.7 (7.5, 7.8)7.8 (7.7, 8.0)7.8 (7.6, 8.0)0.60
 Black8.7 (8.0, 9.5)8.1 (7.5, 8.7)8.2 (7.6, 8.9)8.1 (7.6, 8.7)9.2 (8.3, 10.0)8.4 (7.9, 9.0)8.3 (7.8, 8.7)9.0 (8.4, 9.5)0.21
 Hispanic8.1 (7.6, 8.6)8.0 (7.5, 8.6)7.6 (7.2, 8.1)8.1 (7.7, 8.5)8.2 (7.8, 8.6)7.7 (7.4, 8.0)8.0 (7.6, 8.4)7.9 (7.6, 8.2)0.74
 Other or Unknown9.7 (7.9, 11.5)8.6 (7.4, 9.7)8.5 (7.8, 9.2)7.3 (6.0, 8.7)7.5 (6.8, 8.2)7.8 (7.2, 8.4)7.4 (6.9, 7.9)7.2 (6.4, 8.0)0.002
 White7.7 (7.5, 7.8)7.6 (7.4, 7.7)7.6 (7.5, 7.8)7.4 (7.3, 7.6)7.9 (7.7, 8.1)7.5 (7.4, 7.6)7.7 (7.6, 7.9)7.6 (7.3, 7.8)0.95
Suboptimal :
 Overall63 (14.1)66 (14.0)69 (14.7)66 (14.6)105 (21.7)112 (16.9)120 (19.3)88 (18.1)0.03
 Black16 (40.0)12 (25.5)18 (32.7)15 (31.3)22 (50.0)26 (39.4)27 (30.3)45 (48.4)0.10
 Hispanic11 (26.2)14 (29.8)8 (16.0)16 (28.6)18 (28.1)19 (17.8)25 (27.8)24 (20.5)0.49
 Other or Unknown5 (38.5)4 (30.8)7 (43.8)1 (14.3)1 (5.9)2 (12.5)4 (13.3)2 (11.1)0.03
 White31 (8.8)36 (9.9)36 (10.4)34 (9.9)64 (17.8)65 (13.7)64 (16.2)17 (11.4)0.12

Abbreviation: HbA1c: hemoglobin A1c; ADA: American Diabetes Association. Data were obtained from SEARCH participants with type 1 diabetes who had a baseline visit and a hemoglobin A1c measurement within 30 months of diagnosis. Results were computed using weighted survey procedures. For categorical variables, counts are unweighted, but proportions are weighted. Other race includes Asian/Pacific Islander, Native American, and Other race.