Clinical Characteristics of Target Organ Damage in Primary Aldosteronism with or without Metabolic Syndrome

Table 1

The clinical and biochemical baseline of the PA patients with or without MS.

Characteristic	Without MS ()	With MS ()	value
Sex (male, %)	30.40	58.40	<0.001
Age (y)			<0.001
BMI (kg/m^2)	23.8 (22.3-25.7)	26.5 (25-29.7)	<0.001
WC (cm)			<0.001
SBP (mmHg)	131 (144-157)	146 (133-156)	0.39
DBP (mmHg)			0.09
Total cholesterol (mmol/L)			0.95
Triglycerides (mmol/L)	1.11 (0.81-1.44)	2.01 (1.48-2.57)	<0.001
HDL (mmol/L)			<0.001
LDL (mmol/L)			0.55
IGT/DM (, %)	14 (9.4)	78 (69.0)	<0.001
Uric acid (μmol/L)	286 (235.15-334.75)	338.55 (289.12-388.55)	<0.001
PAC (ng/dl)	20.1 (16.0-25.0)	19.6 (16.0-23.0)	0.19
PRA (ng/ml/h)	0.50 (0.1-1.0)	0.52 (0.12-1.1)	0.87
Serum potassium (mmol/L)			0.51
Antihypertensive drugs ()			0.15

Data are expressed as the , median (25th–75th percentiles), or raw numbers. , , and . PA: primary aldosteronism; MS: metabolic syndrome; BMI: body mass index; SBP: systolic blood pressure; DBP: diastolic blood pressure; HDL: high-density lipoprotein cholesterol; LDL: low-density lipoprotein cholesterol; DM: diabetes mellitus; IGT: impaired glucose tolerance; PAC: plasma aldosterone concentration; PRA: plasma renin activity; WC: waist circumstance.