Research Article
Retinal Thickness Associates with Cognition Dysfunction in Young Adult with Type 1 Diabetes in Taiwan
Table 1
Demographic, clinical, and ophthalmic variables between different groups of age at onset in patients with T1D in this study.
| | Variable | Age at years old (), median (IQR) | Age at years old (), median (IQR) | value |
| | Age (year) | 22.2 (19.7-25.5) | 26.1 (23.5-29.3) | <0.01 | | Gender (M:F) | 18 : 11 | 32 : 46 | 0.05 | | Age at onset (year) | 2.3 (1.4-3.7) | 9.4 (6.8-12.7) | <0.01 | | Disease duration (year) | 20 (17-23) | 15.9 (13.3-19.2) | <0.01 | | Education (year) | 16 (12-16) | 16 (12-16) | 0.02 | | BMI (kg/m2) | 22.5 (19.4-26.0) | 22.5 (20.5-26.4) | 0.66 | | HbA1c_5 (%) | 8.1 (7.4-9.3) | 7.8 (6.9-8.6) | 0.07 | | HbA1c_10 (%) | 8.5 (7.3-9.7) | 8.2 (7.2-9) | 0.15 | | Creatine (mg/dL) | 0.63 (0.52-0.79) | 0.66 (0.58-0.84) | 0.27 | | HS_CRP (mg/L) | 0.63 (0.26-1.67) | 0.74 (0.36-1.94) | 0.55 | | Homocysteine (μmol/L | 9 (7.0-10.4) | 8.6 (7.1-10.5) | 0.53 | | LogMAR VA_OD | 0 (0-0.09) | 0 (0-0.05) | 0.28 | | LogMAR VA_OS | 0 (0-0) | 0 (0-0) | 0.83 | | AXL_OD (mm) | 24.7 (23.7-25.6) | 24.7 (23.6-25.7) | 0.85 | | AXL_OS (mm) | 24.7 (23.9-25.5) | 24.7 (23.6-25.6) | 0.85 | | CRT_OD (μm) | 266.5 (256-278) | 265 (255-282) | 0.95 | | CRT_OS (μm) | 263 (256.5-282.5) | 266 (255-278.7) | 0.97 | | Severity of diabetic retinopathy_OD | | | 0.83 | | 0 | 21 | 63 | | | 1 | 5 | 9 | | | 2 | 2 | 4 | | | 3 | 1 | 2 | | | Severity of diabetic retinopathy_OS | | | 0.99 | | 0 | 21 | 58 | | | 1 | 5 | 13 | | | 2 | 2 | 5 | | | 3 | 1 | 2 | |
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IQR: interquartile range; BMI: body mass index; HbA1c: glycated hemoglobin; HS_CRP: high-sensitive C-reactive protein; LogMAR VA: logarithm of the minimum angle of resolution visual acuity; AXL: axial length; CRT: central retinal thickness; OD: oculus dexter; OS: oculus sinister.
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