Research Article

Retinal Thickness Associates with Cognition Dysfunction in Young Adult with Type 1 Diabetes in Taiwan

Table 3

Comparison of clinical and ophthalmic variables between patients with and without diabetic retinopathy in T1D.

VariableDiabetic retinopathy group (), median (IQR)No diabetic retinopathy group (), median (IQR) value

Age (year)26.4 (23.3-29.4)24.5 (21.7-27.7)0.08
Gender (M:F)6 : 1239 : 400.22
Age at onset (year)8.3 (4.4-11.8)7.2 (4.2-11.6)0.65
Disease duration (year)17.8 (15.7-25.7)16.7 (13.3-20)0.12
Education year (year)16 (16-16)16 (12-16)0.12
BMI (kg/m2)24.8 (20.3-26.8)22.4 (19.9-25.9)0.38
HbA1c_5 (%)8.7 (7.8-10)7.6 (6.9-8.2)<0.01
HbA1c_10 (%)9.1 (8.2-10.4)7.9 (7.1-8.7)<0.01
Creatine (mg/dL)0.63 (0.52-0.71)0.69 (0.58-0.83)0.03
HS_CRP (mg/L)1.28 (0.42-2.3)0.61 (0.27-1.54)0.03
Homocysteine (μmol/L)8.4 (6.8-10)8.8 (7.3-10.7)0.23
LogMAR VA_OD0 (0-0.09)0 (0-0)<0.01
LogMAR VA_OS0 (0-0.15)0 (0-0)<0.01
AXL_OD (mm)23.9 (22.9-25.1)24.9 (23.9-25.8)<0.01
AXL_OS (mm)24.0 (22.9-24.9)24.8 (23.9-25.8)<0.01
CRT_OD (μm)260 (247-278)267 (256-282)0.12
CRT_OS (μm)263 (254-281)266 (255-279)0.70

BMI: body mass index; HbA1c: glycated hemoglobin; HS_CRP: high-sensitive C-reactive protein; LogMAR VA: logarithm of the minimum angle of resolution visual acuity; AXL: axial length; CRT: central retinal thickness; OD: oculus dexter; OS: oculus sinister.