Research Article
Interaction of Hypertension and Insulin Resistance Exacerbates the Occurrence of Diabetes Mellitus in Healthy Individuals
Table 1
Baseline characteristics of study participants [
or median (IQR) or
].
| | Characteristics | Total
( =1251) | Blood pressure classification(mmHg) | value | | <130/80 ( =368) | 130-139/80-89 ( =236) | ≥140/90 or treated ( =647) |
| | Age (y) | 63.2 ± 10.2 | 59.3 ± 8.9 | 61.1 ± 9.6 | 66.1 ± 10.3 | <0.001 | | Gender (male/female) | 462/789 | 112/256 | 81/155 | 269/378 | 0.001 | | Systolic blood pressure (mmHg) | 135.8 ± 18.8 | 116.9 ± 8.6 | 131.7 ± 6.0 | 148.0 ± 16.4 | <0.001 | | Diastolic blood pressure (mmHg) | 76.9 ± 11.0 | 69.0 ± 6.4 | 77.4 ± 7.7 | 81.3 ± 11.6 | <0.001 | | Fasting blood glucose (mmol/L) | 5.3 ± 1.1 | 5.0 ± 0.8 | 5.3 ± 0.9 | 5.5 ± 1.2 | <0.001 | | Postprandial blood glucose (mmol/L) | 7.6 ± 3.4 | 6.4 ± 2.6 | 7.3 ± 3.0 | 8.4 ± 3.7 | <0.001 | | Total cholesterol (mmol/L) | 5.1 ± 0.9 | 5.1 ± 0.9 | 5.1 ± 0.9 | 5.1 ± 1.0 | 0.789 | | Triglycerides (mmol/L) | 1.7 ± 1.1 | 1.5 ± 0.8 | 1.7 ± 1.2 | 1.8 ± 1.2 | <0.001 | | LDL-C (mmol/L) | 3.0 ± 0.8 | 3.0 ± 0.8 | 2.9 ± 0.8 | 3.0 ± 0.8 | 0.779 | | HDL-C (mmol/L) | 1.4 ± 0.4 | 1.5 ± 0.4 | 1.4 ± 0.4 | 1.4 ± 0.4 | 0.001 | | Abdominal circumference (cm) | 83.4 ± 9.7 | 79.7 ± 8.5 | 82.6 ± 8.5 | 85.8 ± 10.0 | <0.001 | | Diabetes (yes/no) | 166/1085 | 18/350 | 25/211 | 123/524 | <0.001 | | Proportion of diabetic patients (%) | 13.3 | 4.9 | 10.6 | 19.0 | <0.001 | | HOMA-IR | 1.8 (1.2-2.7) | 1.4 (0.9-2.0) | 1.9 (1.3-2.6) | 2.0 (1.3-3.1) | <0.001 |
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