Interaction of Hypertension and Insulin Resistance Exacerbates the Occurrence of Diabetes Mellitus in Healthy Individuals

Table 2

The odds ratio (OR) of new-onset diabetes with different BP and HOMA-IR levels [OR (95% CI)].

	Model 1; OR (95% CI)		Model 2; OR (95% CI)		Model 3; OR (95%)
Blood pressure (mmHg)
<130/80	1		1		1
130-139/80-89	1.680 (0.877-3.218)	0.118	1.541 (0.797-2.979)	0.199	1.473 (0.760-2.856)	0.252
≥140/90 or treated	2.956 (1.736-5.032)	<0.001	2.432 (1.407-4.202)	0.001	2.230 (1.283-3.876)	0.004
HOMA-IR
<1.21	1		1		1
1.21-1.81	1.529 (0.730-3.201)	0.260	1.560 (0.737-3.300)	0.245	1.401 (0.658-2.985)	0.382
1.81-2.68	2.846 (1.445-5.606)	<0.002	3.036 (1.535-6.005)	0.001	2.495 (1.231-5.055)	0.011
≥2.68	8.651 (4.585-16.325)	<0.001	9.670 (5.086-18.384)	<0.001	7.049 (3.479-14.285)	<0.001