Research Article

Nutritional Interventions May Improve Outcomes of Patients Operated on for Diabetic Foot Infections: A Single-Center Case-Control Study

Table 1

Characteristics of 1,013 patients operated on for diabetic foot infections.

RemissionClinical failure
Characteristic () (75%) (25%) value

Male sex203 (80%)591 (78%)0.58
Median age65 years68 years0.09
Insulin therapy561 (74%)197 (75%)0.69
Diabetic foot osteomyelitis present213 (84%)669 (88%)0.06
Undergoing renal dialysis63 (8%)22 (9%)0.88
Congestive heart failure174 (23%)83 (33%)0.01
Moderate to severe limb ischemia559 (74%)205 (80%)0.03
Active tobacco smoker445 (59%)162 (64%)0.17
Number of surgical debridement (median)110.01
Duration of antibiotic therapy (median)20 days30 days0.01
 Parenteral route of therapy (median)4 days7 days0.01
Nutritional assessments on admission
Median NRS-Score2 points3 points0.82
Median weight87 kg86 kg0.75
Median body mass index28.7 kg/m229.5 kg/m20.46
Reported weight loss54 (7%)20 (8%)0.70
Median weight loss in the last 2 months5 kg5 kg0.84
Median serum albumin level+39 mg/L31 mg/L0.02
Regular alcohol consumption173 (23%)70 (27%)0.13
Nutrition interventions during hospitalization
At least one nutritionist’s counselling142 (19%)49 (19%)0.87
Overall number of nutritionists’ interventions110.80
Supplementation with vitamins190 (25%)61 (24%)0.71

Pearson test or Wilcoxon rank sum tests. Significant results () are in bold. += more likely to be influenced by the presence of infection rather than the nutrition level; NRS = Nutritional Risk Screening Score 2002.