The Potential Therapeutic Effect of Orexin-Treated versus Orexin-Untreated Adipose Tissue-Derived Mesenchymal Stem Cell Therapy on Insulin Resistance in Type 2 Diabetic Rats

Table 3

Levels of glucose uptake, lipid profile, and inflammatory markers in different study groups.

Variables	Control group	T2DM group	AD-MSCs group	AD-MSCs pretreated with OXA group
Glucose uptake
Muscle (mg/g tissue/h)		^a	^abc	^b
Adipose tissue (mg/g tissue/h)		^a	^abc	^b
Lipid profile
Triglycerides (mg/dl)		^a	^abc	^b
Total cholesterol (mg/dl)		^a	^abc	^b
HDL (mg/dl)		^a	^abc	^b
Inflammatory markers
TNF-α (pg/ml)		^a	^abc	^b
IL-6 (pg/ml)		^a	^abc	^b

The results are reported as ; each. as compared to the control group, as compared to the T2DM group, and as compared to AD-MSCs pretreated with the OXA group. T2DM group/T2DM: type 2 diabetes; AD-MSCs: adipose-derived mesenchymal stem cells; OXA: orexin A. The significance level was set at .