Research Article
Diabetes Management and Outcomes among Patients with Type 2 Diabetes Attending a Renal Service
Table 2
Metabolic target and renal parameters data according to insulin treatment status.
| | Total | Insulin treated | Noninsulin treated | |
| | HbA1c | | | | | | (%; mmol/mol) | ; 57 | ; 64 | ; 51 | <0.001 | | By CKD stage, (%; mmol/mol) | | | | 0.770§ | | Stage 1 | ; 53 | | | | | Stage 2 | ; 61 | | | | | Stage 3a | ; 60 | | | | | Stage 3b | ; 57 | | | | | Stage 4 | ; 56 | | | | | Stage 5 | ; 58 | | | | | ≤7.0% (53 mmol/mol), (%) | 114/224 (50.9) | 35/110 (31.8) | 79/114 (69.3) | <0.001 | | ≤8.0% (64 mmol/Mol), (%) | 158/224 (70.5) | 59/110 (53.6) | 99/114 (86.8) | <0.001 | | SBP (mmHg), | | | | 0.687 | | DBP (mmHg), | | | | 0.738 | | BP ≤130/80 mmHg, (%) | 151/265 (57.0) | 76/122 (62.3) | 75/143 (52.4) | 0.107 | | ≤140/80 mmHg, (%) | 211/265 (79.6) | 99/122 (81.1) | 112/143 (78.3) | 0.569 | | TC (mmol/L), | | | | 0.571 | | <4.0 mmol/L, (%) | 111/199 (55.8) | 52/96 (54.2) | 59/103 (57.3) | 0.658 | | TG (mmol/L), geometric mean | 1.8 | 2.0 | 1.7 | 0.069 | | <2.0 mmol/L, (%) | 111/195 (56.9) | 49/94 (52.1) | 62/101 (61.4) | 0.192 | | LDL (mmol/L), | | | | 0.064 | | <2.0 mmol/L, (%) | 69/130 (53.1) | 35/64 (54.7) | 34/66 (51.5) | 0.717 | | HDL (mmol/L), | | | | 0.001 | | ≥1.0 mmol/L, (%) | 89/159 (56.0) | 37/83 (44.6) | 52/76 (68.4) | 0.002 | | BMI (kg/m2), | | | | 0.028 | | 18.5-24.9 kg/m2, (%) | 18/192 (9.4) | 6/94 (6.4) | 12/98 (12.2) | 0.164 | | Renal parameters data | | | | | | eGFR (mL/min/1.73 m2), median (min; max) | 33 (3; 90) | 26 (3; 90) | 38 (4; 90) | <0.001 | | Rate of change eGFR/year (mL/min/1.73 m2/year), median (min; max) | -3.0 (-64; 28) | -5.0 (-64; 22) | -2.0 (-40; 28) | 0.001‡ | | UACR (mg/mmol) | | | | | | Median (min; max) | 23.4 (0.3; -1080) | 76.3 (0.7; 812.7) | 14.0 (0.3; 1080) | <0.001‡ | | Within normal range (women) | | | | | | <3.5 mg/mmol; men <2.5 mg/mmol) | 30/159 (18.9) | 5/72 (7.0) | 25/87 (28.7) | <0.001 | | Rate of change UACR/year (mg/mmol/year), median (min; max) | -0.5 (-580.7; 273.0) | -2.1 (-295.6; 273.0) | -0.2 (-580.7; 204) | 0.611‡ | | Haemoglobin (g/L), | | | | 0.288 |
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Independent -test, unless otherwise stated. §ANOVA. ‡Mann–Whitney test. HbA1c: glycated haemoglobin; SBP: systolic blood pressure; DBP: diastolic blood pressure; BP: blood pressure; TC: total cholesterol; TG: triglycerides; LDL: low density lipoprotein; HDL: high density lipoprotein; BMI: body mass index; eGFR: estimated glomerular filtration rate; UACR: urine albumin creatinine ratio; Hb: haemoglobin; min: minimum value; max: maximum value. |
