Epigenetic Changes Induced by High Glucose in Human Pancreatic Beta Cells

Figure 1

% Cell viability using MTT assay. No negative effect was observed on cell morphology or growth kinetics at or below 15 mM, but at a concentration of 20 mM, a cytotoxic effect was noted. A 15 mM solution of glucose was determined to be the maximum concentration that could be used without inducing cell death.