Epigenetic Changes Induced by High Glucose in Human Pancreatic Beta Cells

Figure 14

Celecoxib. This molecule has a role in cell expression in apoptosis, proliferation, growth, phosphorylation, cell death, survival, G1 phase, and activation. Celecoxib is at the center, and the dotted lines with arrows indicate downstream target genes that are upregulated (red) or downregulated (green) due to differential methylation as indicated in our dataset. The meaning of line and arrow style is the same as for Figure 10.