Journal of Diabetes Research

Diabetic Endothelium Dysfunction, Cardiovascular Complications, and Therapeutics


Status
Published

Lead Editor

1Oklahoma Medical Research Foundation, Oklahoma City, USA

2Charles Drew University, Los Angeles, USA

3Yeungnam University, Daegu, Republic of Korea

4Shandong University, Jinan, China


Diabetic Endothelium Dysfunction, Cardiovascular Complications, and Therapeutics

Description

Diabetes and its complications are becoming an emerging pandemic. Vascular endothelial cells play a major role in maintaining vascular homeostasis. Dysfunction of the vascular endothelium is a critical factor in the pathogenesis of diabetic micro- and macrovascular diseases. The fundamental mechanism contributing to vascular disease, nephropathy, retinopathy, and neuropathy has yet to translate into effective therapeutics. Uncovering novel mechanism governing endothelium dysfunction, new concepts about biological pathways involved in diabetic tissue injury and identification of new therapeutics are of significance. Circulating endothelial progenitor cells (EPCs) in diabetes are reduced and are dysfunctional, suggesting EPC as a biomarker for diabetes and a prospective approach for regenerative medicine.

In this special issue, investigators are invited to publish their original research as well as review articles on the role of endothelial dysfunction in the etiology and pathogenesis of the micro- and macrovascular complications of diabetes, as well as therapeutic practice.

Potential topics include, but are not limited to:

  • Novel molecular mechanism of hyperglycemia on endothelial dysfunction and complications
  • Stress signaling in diabetic endothelial dysfunction and complications
  • Diabetic retinopathy and renal microangiopathy
  • Diabetic atherosclerosis, coronary, carotid, and peripheral arteries
  • Therapeutic approaches including EPC for diabetic endothelium repair
  • Diabetic vascular injury, vascular remodeling, and wound healing

Articles

  • Special Issue
  • - Volume 2016
  • - Article ID 5349801
  • - Editorial

Diabetic Endothelium Dysfunction, Cardiovascular Complications, and Therapeutics

Yunzhou Dong | Yong Wu | ... | Shuangxi Wang
  • Special Issue
  • - Volume 2016
  • - Article ID 4158591
  • - Research Article

Curcumin Protects Neonatal Rat Cardiomyocytes against High Glucose-Induced Apoptosis via PI3K/Akt Signalling Pathway

Wei Yu | Wenliang Zha | ... | Chao Liu
  • Special Issue
  • - Volume 2016
  • - Article ID 3789217
  • - Review Article

Diabetic Retinopathy: Animal Models, Therapies, and Perspectives

Xue Cai | James F. McGinnis
  • Special Issue
  • - Volume 2016
  • - Article ID 1748065
  • - Research Article

Vitamin B6 Prevents Endothelial Dysfunction, Insulin Resistance, and Hepatic Lipid Accumulation in Apoe−/− Mice Fed with High-Fat Diet

Zhan Liu | Peng Li | ... | Shuang-Xi Wang
  • Special Issue
  • - Volume 2016
  • - Article ID 3271293
  • - Research Article

Effect of Vitamins C and E on Endothelial Function in Type 1 Diabetes Mellitus

Rachel-Marie Cazeau | Hong Huang | ... | Robert P. Hoffman
  • Special Issue
  • - Volume 2016
  • - Article ID 1602083
  • - Clinical Study

Effect of Acarbose on Long-Term Prognosis in Acute Coronary Syndromes Patients with Newly Diagnosed Impaired Glucose Tolerance

Peng Yun | Ai-ming Du | ... | Hu Xiao
  • Special Issue
  • - Volume 2016
  • - Article ID 1802036
  • - Research Article

Inhibition of NA+/H+ Exchanger 1 Attenuates Renal Dysfunction Induced by Advanced Glycation End Products in Rats

Peng Li | Geng-Rong Chen | ... | Shuang-Xi Wang
  • Special Issue
  • - Volume 2016
  • - Article ID 6384759
  • - Research Article

Coenzyme Q10 Attenuates High Glucose-Induced Endothelial Progenitor Cell Dysfunction through AMP-Activated Protein Kinase Pathways

Hsiao-Ya Tsai | Chih-Pei Lin | ... | Shing-Jong Lin
  • Special Issue
  • - Volume 2016
  • - Article ID 4385312
  • - Research Article

Impact of Real-Time Continuous Glucose Monitoring Use on Glucose Variability and Endothelial Function in Adolescents with Type 1 Diabetes: New Technology—New Possibility to Decrease Cardiovascular Risk?

Milena Jamiołkowska | Izabela Jamiołkowska | ... | Barbara Głowińska Olszewska
  • Special Issue
  • - Volume 2016
  • - Article ID 1643496
  • - Review Article

Gliptins and Cardiovascular Outcomes: A Comparative and Critical Analysis after TECOS

Samit Ghosal | Binayak Sinha
Journal of Diabetes Research
 Journal metrics
Acceptance rate32%
Submission to final decision68 days
Acceptance to publication26 days
CiteScore5.500
Impact Factor2.965
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