Journal of Diabetes Research

Inflammation and Oxidative Stress in Obesity, Metabolic Syndrome, and Diabetes


Publishing date
29 Jun 2012
Status
Published
Submission deadline
10 Feb 2012

Guest Editors

1Department of Pediatrics, University of California, Irvine, CA, USA

2Department of Sports Medicine, Norwegian School of Sport Sciences, Oslo, Norway

3Department of Pediatrics, Sackler Faculty of Medicine, Tel Aviv University, Ramal Aviv, Israel


Inflammation and Oxidative Stress in Obesity, Metabolic Syndrome, and Diabetes

Description

The continuous rise of incidence and prevalence of obesity, metabolic syndrome, and diabetes is an unprecedented global health concern. These conditions all lead to long-term cardiovascular complications related to impaired lifestyle and work productivity, as well as early death from coronary artery disease, stroke, and renal failure.

The pathogenesis of these micro- and macrovascular complications is complex, but disregulated inflammation and oxidative stress play a dominant role. The numerous involved mediators and biochemical pathways, their activation, response to stimuli, and responsiveness to therapy remain poorly defined. Gaining in-depth and definitive knowledge on these issues is an indispensable prerequisite to develop evidence-based prevention, management, and treatment.

We invite investigators to contribute original research and review articles that will stimulate the understanding of molecular events biochemically linking inflammation, oxidative stress, obesity, metabolic syndrome, and diabetes, as related to the evolution of cardiovascular disease. Potential topics include, but are not limited to:

  • Definition of novel biomarkers of inflammation/oxidative stress in these conditions
  • Standardization of current methodologies to assess inflammation and oxidative stress (cytokines, chemokines, etc.) across large population studies
  • Characterization of specific patterns of functional alteration in immune cells
  • Effects of age on aggressiveness of inflammatory and oxidative processes (early childhood versus later onset)
  • Role of gene expression/epigenetics in inflammatory/oxidative stress pathways
  • Interaction of inflammation, oxidative stress, and exercise (optimization of exercise intensity/formats)
  • The role of chronic anti-inflammatory therapy
  • Correlations between early vascular alterations and increased inflammation/oxidative stress

Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/jdr/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2012
  • - Article ID 943706
  • - Editorial

Inflammation and Oxidative Stress in Obesity, Metabolic Syndrome, and Diabetes

Pietro Galassetti
  • Special Issue
  • - Volume 2012
  • - Article ID 683680
  • - Review Article

Aspects of Inflammation and Oxidative Stress in Pediatric Obesity and Type 1 Diabetes: An Overview of Ten Years of Studies

Brian Tran | Stacy Oliver | ... | Pietro Galassetti
  • Special Issue
  • - Volume 2012
  • - Article ID 815098
  • - Clinical Study

Impact of Insulin Resistance on Silent and Ongoing Myocardial Damage in Normal Subjects: The Takahata Study

Taro Narumi | Tetsuro Shishido | ... | Isao Kubota
  • Special Issue
  • - Volume 2012
  • - Article ID 510902
  • - Research Article

Circulating TGF-β1, Glycation, and Oxidation in Children with Diabetes Mellitus Type 1

Vladimír Jakuš | Michal Sapák | Jana Kostolanská
  • Special Issue
  • - Volume 2012
  • - Article ID 504693
  • - Research Article

Antioxidant Sol-Gel Improves Cutaneous Wound Healing in Streptozotocin-Induced Diabetic Rats

Yen-Hsien Lee | Jung-Jhih Chang | ... | Hsiung-Fei Chien
  • Special Issue
  • - Volume 2012
  • - Article ID 128694
  • - Research Article

Decreased Skin-Mediated Detoxification Contributes to Oxidative Stress and Insulin Resistance

Xing-Xing Liu | Chang-Bin Sun | ... | Shi-Sheng Zhou
  • Special Issue
  • - Volume 2012
  • - Article ID 847246
  • - Research Article

Increased Hypothalamic Inflammation Associated with the Susceptibility to Obesity in Rats Exposed to High-Fat Diet

Xiaoke Wang | Aiguo Ge | ... | Nianhong Yang
  • Special Issue
  • - Volume 2012
  • - Article ID 120645
  • - Research Article

Early Degenerative Effects of Diabetes Mellitus on Pancreas, Liver, and Kidney in Rats: An Immunohistochemical Study

Mehmet Haligur | Senay Topsakal | Ozlem Ozmen
  • Special Issue
  • - Volume 2012
  • - Article ID 905683
  • - Research Article

Effects of Rosiglitazone with Insulin Combination Therapy on Oxidative Stress and Lipid Profile in Left Ventricular Muscles of Diabetic Rats

Servet Kavak | Lokman Ayaz | Mustafa Emre
  • Special Issue
  • - Volume 2012
  • - Article ID 859395
  • - Research Article

A Comparison of Inflammatory and Oxidative Stress Markers in Adipose Tissue from Weight-Matched Obese Male and Female Mice

Karen J. Nickelson | Kelly L. Stromsdorfer | ... | James W. Perfield
Journal of Diabetes Research
 Journal metrics
Acceptance rate31%
Submission to final decision71 days
Acceptance to publication25 days
CiteScore3.020
Impact Factor3.040
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